Tory Brennan is as fascinated by bones and dead bodies as her famous aunt, acclaimed forensic anthropologist, Tempe Brennan. However living on a secluded island off Charleston in South Carolina there is not much opportunity to put her knowledge to the test. Until she and her group of technophile friends stumble across a shallow grave containing the remains of a girl who has been missing for over thirty years. With the cold-case murder suddenly hot, Tory realises that they are involved in something fatally dangerous. And when they rescue a sick dog from a laboratory on the same island, it becomes evident that somehow the two events are linked. On the run from forces they don't understand, they have only each other to fall back on. Until they succumb to a mysterious infection that heightens their senses and hones their instincts to impossible levels. Their illness seems to have changed their very biology - and suddenly it's clear that the island is home to something well beyond their comprehension. It's a secret that has driven men to kill once. And will drive them to kill again...